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Diabetes in cats, day to day

The emergency signs to know first, the glucose targets vets use for cats, why remission changes everything, and what a day curve tells your vet.Updated November 1, 2026

Emergencies first

The two things to recognize immediately

Learn these before you need them. Both can arrive at 2am.

Low blood sugar (hypoglycaemia)

The risk that comes with treatment, and the one that moves fastest. Most often after a dose given when the cat did not eat, a dose given twice, or a cat going into remission while still on the old dose.

Weak or wobbly, shaking, glassy-eyed or confused, then collapse or a seizure. Below 60 mg/dL (3.3 mmol/L) is an emergency: if your cat can eat, offer its usual food; if it is too weak to eat, rub a little corn syrup or honey on the gums with a finger and never pour liquid into the mouth. Give no insulin, and call the vet now.

Diabetic ketoacidosis (DKA)

Builds over hours to days when too little insulin is working, and it is life-threatening.

Vomiting, not eating, marked lethargy, fast breathing and a sweet or nail-polish smell on the breath. On the once-daily oral medicines (bexagliflozin, velagliflozin), DKA can happen with a normal glucose reading, so these signs mean call the vet now, whatever the meter says.

Source: AAHA Diabetes Management Guidelines 2018 · Merck Veterinary Manual · FDA product labels (bexagliflozin, velagliflozin)

In FelineSense

Every dose and every reading, kept for the vet

  • Insulin or a once-daily oral medicine (bexagliflozin, velagliflozin), with the dose copied exactly as your vet wrote it. The app never calculates, suggests or changes a dose
  • A did-your-cat-eat check before each dose, with given, reduced or skipped, and your vet’s instruction for a missed meal kept word for word
  • Readings in mg/dL or mmol/L, each with a plain verdict against the feline targets
  • Injection sites that rotate through the sides, flanks and hips, and an opened-vial countdown from the label
  • The emergency signs one tap away, and a diabetes section in the vet report. See all three chronic conditions
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The FelineSense diabetes screen: today’s insulin doses, the opened-vial countdown, and the latest glucose reading with its verdict

Day to day

What managing feline diabetes involves

The prescribed insulin or oral medicine at the same times each day, regular measured meals, glucose checks at home, and knowing the signs of low blood sugar.

Remission is possible in cats

Most diabetic cats have a form much like type 2 diabetes in people: the body still makes some insulin but responds to it poorly, and obesity is the biggest risk factor. Unlike dogs, many diabetic cats can go into remission and stop needing insulin. It is most likely when good control starts soon after diagnosis, alongside the low-carbohydrate, high-protein diet your vet recommends.

The catch: a cat heading into remission needs less insulin, and the old dose can push it too low. Falling numbers are a reason to call your vet about the dose, never to change it yourself.

Source: AAHA Diabetes Management Guidelines 2018 · Cornell Feline Health Center

The glucose numbers vets use for cats

In a diabetic cat, AAHA aims for glucose of roughly 80–300 mg/dL (4.4–16.7 mmol/L) through the day, with the lowest point, the nadir, ideally 80–150 mg/dL (4.4–8.3 mmol/L). A healthy cat runs about 70–150 mg/dL.

Stress raises a cat’s glucose: a healthy cat at the clinic can read 200–300 mg/dL. That is why readings taken calmly at home, and the fructosamine blood test, which reflects the past one to two weeks, matter so much. Use a pet glucose meter set to the cat code: human meters read low in cats.

Source: AAHA Diabetes Management Guidelines 2018 · Merck Veterinary Manual

Food first, then insulin

Insulin lowers blood sugar whether or not there is food to work on. So the order matters: confirm your cat ate, then give the dose. If your cat refuses a meal, follow the standing instruction your vet gave you for that situation, and call; never give the usual dose and hope. A cat that stops eating for more than a day also risks fatty liver disease (hepatic lipidosis). FelineSense asks whether your cat ate the meal before it logs an injection, and keeps your vet’s instruction word for word.

Source: AAHA Diabetes Management Guidelines 2018

The day curve, and why your vet keeps asking for it

A single reading could be the peak, the low point or anywhere between. A curve is a series of readings across one day, about every 2 hours for 12 hours, and its lowest point, the nadir, together with when it falls, tells your vet whether the dose and timing are right. From memory or scribbled notes it is nearly useless; plotted properly it is the most valuable thing you can bring to an appointment.

Source: AAHA Diabetes Management Guidelines 2018

Insulin, oral medicines and the open vial

Most diabetic cats are treated with a long-acting insulin such as glargine or protamine zinc insulin (PZI), given twice a day. Two once-daily oral medicines, bexagliflozin (Bexacat) and velagliflozin (Senvelgo), are FDA-approved for cats not previously treated with insulin.

An opened insulin vial or pen lasts a limited number of days, set by its label: for example 28 days for glargine, and 60 or 80 days for veterinary PZI depending on the vial size. Past that it loses strength quietly, which looks exactly like control drifting for no reason. Note the date you open it, handle it gently, store it as the label says, and never freeze it.

Source: AAHA 2018 · FDA product labels

Consistency beats precision

Same food, same amounts, same times, every day. Your cat’s dose was set against a routine, so changing the routine changes what the dose does. Write down the deviations too: the half-eaten meal, the treat, the stressful vet visit, the new food. Those are usually what explains an odd reading.

In the app

The curve your vet asks for

A day of glucose readings in FelineSense plotted as a curve, with the nadir marked
The day curve, with the nadir, peak and average
The FelineSense vet report: the last 14, 30 or 90 days, ready to share before a visit
Doses, readings and day curves go into the vet report

Spotting it

Signs of diabetes in cats

What owners notice first

  • Drinking and peeing more: bigger or more clumps in the litter box, a bowl that empties faster.
  • Weight loss with a good or bigger appetite.
  • Walking flat on the back legs, with the hocks touching the ground, from nerve damage.
  • Risk factors: obesity, inactivity, older age, male sex and long-term steroid treatment.

Drinking more is also a sign of kidney disease and an overactive thyroid, the other two common conditions of older cats. Only blood and urine tests can tell them apart. How much drinking is too much is in the water intake guide.

Source: Cornell Feline Health Center · Merck Veterinary Manual · AAHA 2018

Questions

Frequently asked

What are the first signs of diabetes in cats?
Drinking more, peeing more (bigger or more clumps in the litter box), losing weight while eating well or more than usual, and later, walking flat on the back legs. Any of these is worth a vet visit: diagnosis needs blood and urine tests.
Can a diabetic cat go into remission?
Yes. Many cats stop needing insulin, especially when treatment starts early and they move to the low-carbohydrate, high-protein diet the vet recommends. Remission needs the vet to lower and stop the dose step by step; never reduce it yourself.
What is a normal blood sugar for a cat?
About 70–150 mg/dL in a healthy cat. For a diabetic cat on treatment, AAHA aims for roughly 80–300 mg/dL through the day, with the lowest point ideally 80–150 mg/dL. Below 60 mg/dL is an emergency.
What is a glucose curve and why does my vet want one?
A series of readings across one day, about every 2 hours for 12 hours. Its lowest point, the nadir, and when it falls tell your vet whether the dose and timing are right. A single reading cannot tell a peak from a low point.
Should I give insulin if my cat will not eat?
Call your vet before you give it, and follow the standing instruction they gave you for a missed meal. Insulin lowers blood sugar whether or not there is food, so a full dose on an empty stomach risks a dangerous low. Not eating can also be an early sign of ketoacidosis.
Why is my cat’s glucose so high at the vet?
Stress raises blood sugar in cats, so a healthy cat at the clinic can read 200–300 mg/dL. Readings taken calmly at home, and the fructosamine test, give your vet a truer picture.
Can I use a human glucose meter on my cat?
It is better not to. Human meters tend to read low in cats. Use a veterinary meter set to the cat code, and keep using the same one so the numbers stay comparable.

FelineSense keeps the dose exactly as your vet wrote it, every reading with its verdict, the day curve with its nadir and the vial date, in one record for the vet. It never calculates or changes a dose.

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FelineSense gives you information and organization — not a diagnosis. Every number comes from a published veterinary source, cited on screen. Your vet is always the authority.